Why the study?
Does clonidine alter blood pressure dynamics in spontaneously hypertensive rats?
Does clonidine alter blood pressure dynamics in spontaneously hypertensive rats?
Clonidine has a significant chronic effect on blood pressure dynamics in spontaneously hypertensive rats, suggesting that mechanisms governing blood pressure variations are nonlinear.
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Clonidine may chronically modulate blood pressure dynamics in hypertensive rat models; leaves open translation to human hypertension.
Mestivier et al. (1998) studied this question.
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