Why the study?
Does left-to-right intracardiac shunt increase the heterogeneity of cardiopulmonary blood transit times?
Population
82 patients with suspected left-to-right intracardiac shunt investigated at supine rest
Comparison
Left-to-right intracardiac shunt vs 42 patients with suspected shunt but…
Design
Cross-sectional
Authors
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Shunts show greater transit heterogeneity without immediate clinical implications; leaves open causal mechanisms and outcome relevance pending prospective data.
Does left-to-right intracardiac shunt increase the heterogeneity of cardiopulmonary blood transit times?
Left-to-right intracardiac shunts are associated with increased heterogeneity of cardiopulmonary transit times, likely due to pulmonary capillary recruitment.
Kuikka et al. (1999) studied this question.
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