Why the study?
Does amlodipine or atenolol reduce blood pressure in patients with mild to moderate hypertension compared to placebo?
Population
Patients with mild to moderate hypertension
Comparison
Amlodipine once-daily or Atenolol once-daily vs Placebo
Design
RCT
Follow-up
8 weeks
Authors
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Supports once-daily amlodipine or atenolol in mild-moderate hypertension; confirms sustained 24-hour efficacy in this RCT.
Does amlodipine or atenolol reduce blood pressure in patients with mild to moderate hypertension compared to placebo?
Once-daily dosing with either amlodipine or atenolol significantly reduces blood pressure and is well tolerated in patients with mild to moderate hypertension.
Bruijn et al. (1988) studied this question.
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