Population
Low-passage clinical coxsackie B virus isolates and prototype laboratory strains
Comparison
Antireceptor monoclonal antibodies vs Prototype laboratory strains
Design
Preclinical
Authors
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Supports caution against generalizing receptor use from lab strains; leaves open how isolate variation affects human Coxsackie B pathogenesis.
Clinical isolates of Coxsackie B viruses differ from laboratory strains in their receptor specificity, indicating that receptor usage can vary within a serotype and alter during infection.
Bergelson et al. (1997) studied this question.
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