Why the study?
Does high NaCl loading alter endothelium-dependent and -independent vasodilation in patients with essential hypertension?
Population
29 patients with essential hypertension, classified as salt-sensitive or salt-resistant based on…
Comparison
High NaCl diet (340 mmol/d) for 1 week vs Low NaCl diet (50 mmol/d) for 1 week
Design
Cohort
Follow-up
1 week per diet phase
Authors
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Short-term salt loading does not impair forearm vasodilation in essential hypertension; leaves open chronic effects in salt-sensitive patients.
Does high NaCl loading alter endothelium-dependent and -independent vasodilation in patients with essential hypertension?
Short-term high sodium chloride loading does not impair endothelium-dependent or -independent vasodilation in the forearm vasculature of patients with essential hypertension.
Higashi et al. (2001) studied this question.
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