Why the study?
Does propranolol improve blood pressure and heart rate control in hydrallazine-treated hypertensive patients?
Population
Hypertensive patients treated with hydrallazine (n=6)
Comparison
Propranolol vs Control period (hydrallazine alone)
Design
Case_series
Authors
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May support propranolol addition to hydrallazine for BP control without bradycardia; leaves open catecholamine effects pending controlled trials.
Does propranolol improve blood pressure and heart rate control in hydrallazine-treated hypertensive patients?
The addition of propranolol to hydrallazine in hypertensive patients significantly reduces blood pressure and blocks cold pressor-induced heart rate increases, though it does not alter hydrallazine-induced catecholamine excretion.
Velasco et al. (1978) studied this question.
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