Why the study?
Does ETA-selective endothelin receptor antagonism reduce blood pressure in L-NAME-treated normal rats?
Does ETA-selective endothelin receptor antagonism reduce blood pressure in L-NAME-treated normal rats?
The endothelin system does not significantly contribute to elevated blood pressure following chronic NO synthase inhibition with L-NAME in normal rats.
No takes yet. Share an insight, caveat, or question.
ETA antagonism does not lower BP in L-NAME rats; leaves open endothelin's role in NO synthase inhibition hypertension.
Sventek et al. (1997) studied this question.