Why the study?
Does clonidine improve hemodynamic parameters and neurohormonal activation in patients with congestive heart failure?
Population
n=20 patients with congestive heart failure
Design
Case_series
Follow-up
Up to 1 week
Authors
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Clonidine may aid hemodynamic and neurohormonal parameters in HF; leaves open effects on cardiac output and outcomes.
Does clonidine improve hemodynamic parameters and neurohormonal activation in patients with congestive heart failure?
Sympathetic suppression with clonidine in congestive heart failure reduces preload, heart rate, and arterial pressure, but does not significantly reduce systemic vascular resistance or increase cardiac output.
Manolis et al. (1995) studied this question.
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