Key result
Dynamic handgrip exercise significantly increased early diastole indices in diabetes mellitus patients, including E wave (0.67 to 0.81 m/s) and septal e' velocity (7.17 to 8.50 cm/s).
Why the study?
Patients with diabetes mellitus may exhibit pseudo-normal diastolic relaxation on echocardiography, and conventional exercise echocardiography techniques contain movement artifacts.
Does dynamic handgrip exercise alter left ventricular diastolic echocardiographic parameters in patients with type 2 diabetes mellitus compared to healthy controls?
Population
12 DM patients and 12 controls
Comparison
Dynamic handgrip exercise in DM patients vs controls
Follow-up
3 minutes
Authors
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DHE may unmask diastolic changes during echo in DM; hypothesis-generating for diagnostic protocols.
Does dynamic handgrip exercise alter left ventricular diastolic echocardiographic parameters in patients with type 2 diabetes mellitus compared to healthy controls?
Absolute Event Rate: 8.5% vs 7.17%
p-value: p=0.004
Dynamic handgrip exercise is a feasible stressor during echocardiography that can unmask and enhance early diastolic indices in patients with type 2 diabetes mellitus.
Pott Pongpaopattanakul (2022) studied Diabetes mellitus type 2 (n=24). Dynamic handgrip exercise vs. Rest (baseline) was evaluated on Septal e' velocity in diabetes mellitus patients (p=0.004). Dynamic handgrip exercise significantly increased early diastole indices in diabetes mellitus patients, including E wave (0.67 to 0.81 m/s) and septal e' velocity (7.17 to 8.50 cm/s).
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