Key result
Patients with irritable bowel syndrome exhibit abnormal fingertip blood flow responses measured by continuous-wave Doppler sonography, suggesting the presence of excess sympathetic nervous system activity.
Population
Patients with irritable bowel syndrome (IBS)
Comparison
Evaluation of autonomic nervous system function vs Healthy controls
Design
Review
Authors
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May support sympathetic dysfunction in IBS; leaves open validation of fingertip Doppler before any diagnostic use.
Autonomic nervous system dysfunction, specifically increased sympathetic activity, plays a key role in the pathophysiology of irritable bowel syndrome and can be non-invasively assessed via fingertip blood flow.
Manabe et al. (2009) conducted a review in Irritable bowel syndrome. Autonomic nervous system dysfunction vs. Healthy controls was evaluated. Patients with irritable bowel syndrome exhibit abnormal fingertip blood flow responses measured by continuous-wave Doppler sonography, suggesting the presence of excess sympathetic nervous system activity.
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