Why the study?
Is the D allele of the ACE gene associated with an increased risk of malignant vascular injury?
Population
48 patients with malignant vascular injury and 191 healthy controls
Comparison
Presence of the D allele of the human… vs Absence of the D allele / healthy controls
Design
Case-control
Authors
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Supports ACE D allele–MVI association; hypothesis-generating and should not change practice without prospective validation.
Is the D allele of the ACE gene associated with an increased risk of malignant vascular injury?
Possession of at least one copy of the D allele of the ACE gene is associated with an increased risk of developing malignant vascular injury.
Nicholas J. Mayer (2002) studied this question.
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