Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 30, 2023Epidemiology and HealthOpen Access

Persistent proteinuria was associated with the highest risk of IHD (HR 1.578, 95% CI 1.324-1.881), AMI (HR 2.069, 95% CI 1.281-3.342), and angina pectoris (HR 1.554, 95% CI 1.272-1.899) compared to persistently negative proteinuria.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Do changes in proteinuria status affect the risk of developing ischemic heart disease, acute myocardial infarction, and angina pectoris in adults?

Population

265,236 Korean adults who underwent health checkups

Comparison

Resolved, incident, or persistent proteinuria vs negative proteinuria

Design

Cohort study

Follow-up

6 years

Authors

SPSung Keun ParkJJJu Young JungMKMin Ho Kim

Discussion

Loading...

Member takes

Overview

Proteinuria trajectory may refine CVD risk stratification in primary care; hypothesis-generating and requires prospective validation.

Structured PICO

Do changes in proteinuria status affect the risk of developing ischemic heart disease, acute myocardial infarction, and angina pectoris in adults?

P
Population
265,236 Korean adults who underwent health checkups in 2003-2004 and 2007-2008
I
Intervention
Changes in proteinuria status (resolved: ≥1+ to negative; incident: negative to ≥1+; persistent: ≥1+ to ≥1+)
C
Comparator
Persistently negative proteinuria (negative to negative)
O
Outcome
Incidence of ischemic heart disease (IHD), acute myocardial infarction (AMI), and angina pectorishard clinical

Any experience of proteinuria, even if it resolves, is associated with an increased risk of ischemic heart disease, acute myocardial infarction, and angina pectoris.

Cite This Study

Park et al. (2023) studied this question.

synapsesocial.com/papers/6a852e545e7c61be8d6e1123https://doi.org/10.4178/epih.e2023088
View Full Paper
Ask AI
Bookmark
Share