Why the study?
Does a subpressor dose of arginine vasopressin increase mean arterial pressure in Dahl salt-sensitive rats compared to Brown Norway rats?
Does a subpressor dose of arginine vasopressin increase mean arterial pressure in Dahl salt-sensitive rats compared to Brown Norway rats?
Small elevations of plasma AVP can produce chronic hypertension in Dahl salt-sensitive rats, likely due to reduced medullary NOS enzyme activity.
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Supports AVP role in salt-sensitive rat models; leaves open human translation and clinical relevance.
Yuan et al. (2001) studied this question.
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