Population
Neurovirulent Type I poliovirus and its attenuated mutant
Comparison
Quantitative complement fixation (CF) test vs Neutralization rate
Design
Preclinical
Authors
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May support poliovirus strain differentiation in research; leaves open human diagnostic or vaccine applications.
Quantitative complement fixation can distinguish between virulent and attenuated Type I polioviruses, unlike neutralization rates.
Gerber et al. (1965) studied this question.
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