May 1, 1983Annals of Internal Medicine
Calcium, Vascular Smooth Muscle, and Calcium Entry Blockers in Hypertension
Why the study?
Do calcium entry blockers reduce blood pressure and improve abnormal vasomotion in patients with hypertension?
Population
Patients with hypertension and other cardiovascular disorders
Design
Review
Authors
Discussion
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Member takes
Implication
Mechanistic support for calcium entry blockers in hypertension; leaves open prospective validation of effects on abnormal vasomotion.
Structured PICO
Do calcium entry blockers reduce blood pressure and improve abnormal vasomotion in patients with hypertension?
P
Population
Patients with hypertension and other cardiovascular disorders
I
Intervention
Calcium entry blockers
O
Outcome
Blood pressure reduction and vasomotion improvement
Calcium entry blockers provide a mechanistic approach to treating hypertension by interfering with cellular mechanisms for vasoconstriction.
Cite This Study
Jay N. Cohn (1983) studied this question.