Why the study?
Does timolol reduce platelet aggregation or arrhythmias in patients after myocardial infarction?
Population
10 healthy men and 44 patients after a myocardial infarction
Comparison
Timolol or propranolol vs Corresponding placebo
Design
RCT
Authors
Loading...
Chronic timolol reduces post-MI arrhythmias independently of platelet inhibition; challenges platelet aggregation as the mediating mechanism.
Does timolol reduce platelet aggregation or arrhythmias in patients after myocardial infarction?
The antiarrhythmic benefits of chronic timolol therapy in post-myocardial infarction patients are not mediated by a sustained inhibitory effect on platelet aggregation.
Thaulow et al. (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: