Why the study?
Does naloxone administration reduce blood pressure and improve baroreflex function in hypertensive rats?
Population
Conscious normotensive and two-kidney renovascular hypertensive rats
Comparison
Naloxone administration vs 0.9% NaCl treatment
Design
Preclinical
Follow-up
one week
Authors
Loading...
Naloxone attenuates hypertension via baroreflex in rats; hypothesis-generating for opioid pathways in human renovascular hypertension.
Does naloxone administration reduce blood pressure and improve baroreflex function in hypertensive rats?
Endogenous opiates acting in the brain contribute to the development and maintenance of renovascular hypertension by modulating baroreceptor reflex function.
Julianna E. Szilagyi (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: