Population
1 patient with stage IV sigmoid colon carcinoma
Design
Case_report
Follow-up
11 months
Authors
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Supports vigilance for non-atherosclerotic MI on prolonged 5-FU; leaves open confirmation of cumulative toxic mechanisms.
5-fluorouracil therapy may cause myocardial infarction, potentially due to endoarteritis from an immuno-allergic or toxic cumulative process rather than arteriosclerosis.
Leone et al. (1985) studied this question.
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