Population
CHO cells in vitro
Comparison
Coexpression of BK channel alpha and BKbeta4… vs Smooth muscle BKalpha/beta1 channels
Design
Preclinical
Authors
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Animal data on beta4 BK channels should not change practice; leaves open selective modulation as a research avenue.
The cloning and characterization of hKCNMB3 and hKCNMB4 reveal distinct electrophysiological and pharmacological properties of BK channels containing the beta4 subunit.
Behrens et al. (2000) studied this question.
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