Population
Scrapie-infected mice
Design
Preclinical
Authors
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No support for poly(I:C) in murine scrapie; hypothesis-generating for interferon-prion interactions in other models.
Polyinosinic-polycytidylic acid does not protect against scrapie infection in mice, nor does scrapie alter the interferon response.
Michael Worthington (1972) studied this question.
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