Key result
Testing identical plasma samples from patients on stable oral anticoagulant therapy across three laboratories using different thromboplastins and coagulometers yielded significantly different INR readings (p=0.00).
Why the study?
Do different thromboplastins and coagulometers affect INR readings in patients under stable oral anticoagulant therapy?
Cross-Sectional (n=50)
Yes
Do different thromboplastins and coagulometers affect INR readings in patients under stable oral anticoagulant therapy?
Answers are grounded in this paper and cite their sources.
This study aims to evaluate the impact of different thromboplastins and coagulometers on INR readings in patients on stable oral anticoagulation.
Background: Variations between various thromboplastin preparations have in the past led to decreased accuracy of INR readings. Because thromboplastin reagents vary widely in composition and manner of preparation, their sensitivity in monitoring oral anticoagulant therapy also vary widely. This study aimed to evaluate different thromboplastins and coagulometers on INR reading for patients under stable oral anticoagulant therapy.
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Abdel et al. (2015) conducted a cross-sectional in Stable oral anticoagulant therapy (n=50). Different thromboplastins and coagulometers vs. Comparison among three laboratories was evaluated on Difference in INR readings across three laboratories (p=0.00). Testing identical plasma samples from patients on stable oral anticoagulant therapy across three laboratories using different thromboplastins and coagulometers yielded significantly different INR readings (p=0.00).
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