Population
Rats (unilateral denervation model and two-kidney, one-clip Goldblatt model)
Comparison
Unilateral denervation of the left kidney or… vs Contralateral kidney
Design
Preclinical
Follow-up
7 days
Authors
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Emphasizes intrarenal over plasma ANG II control of glomerular receptors; leaves open translation beyond rodent models.
The intrarenal renin-angiotensin system is a more important modulator of glomerular ANG II receptor density than plasma ANG II.
Wílkes et al. (1988) studied this question.
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