Why the study?
Does captopril attenuate norepinephrine-induced cardiac hypertrophy and hemodynamic changes in rats?
Does captopril attenuate norepinephrine-induced cardiac hypertrophy and hemodynamic changes in rats?
High-dose captopril attenuates norepinephrine-induced cardiac hypertrophy and systolic blood pressure increases in a rat model.
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Captopril effects in this rat model warrant no clinical change; leaves open translation of ACE inhibition to human catecholamine-driven hypertrophy.
Laycock et al. (1996) studied this question.
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