Why the study?
Does beta adrenoceptor inhibition change baroreceptor reflex sensitivity in patients with essential hypertension?
Population
18 patients with essential hypertension
Comparison
Oral timolol for 9 weeks and intravenous… vs 4-week placebo period
Design
Cohort
Follow-up
13 weeks (4 weeks placebo + 9 weeks timolol)
Authors
Loading...
Beta-blockers leave BRS unaltered in essential hypertension; leaves open reflex contributions to their efficacy.
Does beta adrenoceptor inhibition change baroreceptor reflex sensitivity in patients with essential hypertension?
Short- and long-term beta-blocker therapy does not alter baroreceptor reflex sensitivity in patients with essential hypertension.
Simon et al. (1977) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: