Why the study?
Are neutralizing antibodies present in the acute phase serum of poliomyelitis patients at or before the onset of paralysis?
Population
7 poliomyelitis patients, ranging from 2 to 16 years of age
Design
Case_series
Authors
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May indicate early neutralizing antibodies in poliomyelitis; case report leaves open generalizability and clinical relevance.
Are neutralizing antibodies present in the acute phase serum of poliomyelitis patients at or before the onset of paralysis?
Neutralizing antibodies to the infecting strain of poliomyelitis are already present at or before the onset of paralysis.
Hammon et al. (1948) studied this question.
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