Why the study?
Is the Gly460Trp polymorphism of the alpha-adducin gene associated with higher blood pressure and hypertension in a Japanese population?
Is the Gly460Trp polymorphism of the alpha-adducin gene associated with higher blood pressure and hypertension in a Japanese population?
The Gly460Trp polymorphism of the alpha-adducin gene is associated with low renin hypertension in younger Japanese subjects.
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No immediate clinical implications for genotyping; leaves open confirmation of alpha-adducin variants in low-renin hypertension.
Sugimoto et al. (2002) studied this question.
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