Why the study?
Is the alpha-adducin 460 polymorphism associated with an increased risk of essential hypertension in a Japanese population?
Population
170 hypertensive and 194 normotensive Japanese subjects (n=364)
Comparison
Presence of alpha-adducin 460 polymorphism vs Absence of the polymorphism / normotensive…
Design
Case-control
Authors
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Alpha-adducin polymorphism should not guide hypertension risk assessment in Japanese patients; challenges prior associations reported in white populations.
Is the alpha-adducin 460 polymorphism associated with an increased risk of essential hypertension in a Japanese population?
The alpha-adducin 460 polymorphism is not a major genetic risk factor for essential hypertension in the Japanese population, contrasting with previous findings in white populations.
Katsunori ISHIKAWA (1998) studied this question.
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