Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1991International Immunology

Molecular definition of human β2-glycoprotein (α2-GPI) by cDNA cloning and inter-species differences of β2-GPI in alternation of anticardiolipin binding

View Full Paper
Ask AI
Bookmark
Share

Authors

EMEiji MatsuuraMIMakoto IgarashiYIYoshiko Igarashi

Discussion

Loading...

Member takes

Overview

Animal beta2-GPI may confound aCL assays in SLE; leaves open human-specific standardization for diagnostics and research.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Matsuura et al. (1991) studied this question.

synapsesocial.com/papers/6a8ce0f1029556da77eaa258https://doi.org/10.1093/intimm/3.12.1217
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of a region of beta 2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity.1993 · 180 citations
  2. 2Heterogeneity and Immunochemical Properties of Anti-β2-glycoprotein I Autoantibodies1998 · 44 citations
  3. 3Anticardiolipin and Anti-β2-GPI Are Two Distinct Populations of Autoantibodies1996 · 32 citations
  4. 4The fifth domain of <i>beta</i> 2-glycoprotein I contains a phospholipid binding site (Cys281-Cys288) and a region recognized by anticardiolipin antibodies.1994 · 273 citations
  5. 5Antibodies to β<sub>2</sub>‐glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus1996 · 200 citations