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October 1, 1992Avian Diseases

Further Evidence That the Nucleic Acid of Avian Encephalomyelitis Virus Consists of RNA

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Population

Chicken embryo kidney cell cultures infected with the Van Roekel strain of avian encephalomyelitis virus (AEV)

Comparison

5-bromo 2'-deoxyuridine (BUdR) vs Known DNA and RNA viruses as controls

Design

Preclinical

Authors

DSDarren R. ShafrenCalvary Mater Newcastle HospitalGTG. A. TannockThe Royal Melbourne Hospital

Discussion

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Implication

Supports AEV enterovirus classification in avian models; leaves open any clinical or cardiovascular relevance.

Structured PICO

P
Population
Chicken embryo kidney cell cultures infected with the Van Roekel strain of avian encephalomyelitis virus (AEV)
I
Intervention
5-bromo 2'-deoxyuridine (BUdR)
C
Comparator
Known DNA and RNA viruses as controls
O
Outcome
Viral growth inhibitionsurrogate

The nucleic acid of the Van Roekel strain of avian encephalomyelitis virus is RNA, supporting its classification as an Enterovirus.

Cite This Study

Shafren et al. (1992) studied this question.

synapsesocial.com/papers/6a8ce6908a9f77207c301b46https://doi.org/10.2307/1591568
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characterization of Avian Encephalomyelitis Virus (An Avian Enterovirus)1969 · 36 citations
  2. 2A Rapid Procedure for the Purification of Avian Encephalomyelitis Viruses1985 · 11 citations
  3. 3Pathogenesis of avian encephalomyelitis viruses1991 · 14 citations
  4. 4Vero microcultures for adenovirus neutralization tests1978 · 37 citations
  5. 5Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens1984 · 105 citations