Why the study?
Does long-term treatment with procaine amide cause drug-induced SLE syndrome in patients with cardiac arrhythmias?
Population
42 patients with different cardiac arrhythmias
Design
Cohort
Follow-up
up to over 5 years
Authors
Loading...
Monitoring for drug-induced SLE warranted with long-term procaine amide, especially in slow acetylators; supports acetylator phenotyping research but leaves practice implications open.
Does long-term treatment with procaine amide cause drug-induced SLE syndrome in patients with cardiac arrhythmias?
Long-term procaine amide therapy frequently induces ANF and SLE syndrome, particularly in slow acetylators, which typically resolves upon discontinuation.
Henningsen et al. (1975) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: