Key result
Hypoxia significantly increased plasma free dopamine levels compared to normoxia (230 vs 150 pg/ml; P<0.01), whereas normoxic exercise did not, indicating dopamine varies independently of sympathoadrenal activity.
Authors
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May warrant dopamine assessment in hypoxic patients; leaves open its independent role in cardiovascular regulation.
Absolute Event Rate: 230% vs 150%
p-value: p=<0.01
Pequignot et al. (1985) studied this question. Hypoxia and exercise vs. Rest and normoxia was evaluated on Plasma free dopamine levels during hypoxia vs normoxia (p=<0.01). Hypoxia significantly increased plasma free dopamine levels compared to normoxia (230 vs 150 pg/ml; P<0.01), whereas normoxic exercise did not, indicating dopamine varies independently of sympathoadrenal activity.
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