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December 1, 1991AJP Heart and Circulatory Physiology

Myocardial protection by R 56865: a new principle based on prevention of ion channel pathology

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Authors

LDLuc Ver DonckJohnson & Johnson (United States)MBM. BorgersJanssen (Belgium)

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Implication

May identify Ca²⁺ entry routes in isolated myocytes; leaves open in vivo relevance and clinical translation.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Donck et al. (1991) studied this question.

synapsesocial.com/papers/6a90186f17e522ae792b049chttps://doi.org/10.1152/ajpheart.1991.261.6.h1828

Topics

Cardiomyopathy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inhibition of sodium and calcium overload pathology in the myocardium: a new cytoprotective principle1993 · 107 citations
  2. 2Pathophysiology of Cardiomyocytesa1988 · 38 citations
  3. 3Mechanism of protection by verapamil and nifedipine from anoxic injury in isolated cardiac myocytes1984 · 55 citations
  4. 4Cardioprotective Aspects of Calcium Antagonists1991 · 4 citations
  5. 5Consequences of uncontrolled calcium entry and its prevention with calcium antagonists1983 · 61 citations