Why the study?
Does continuous intravenous infusion of synthetic bradykinin alter systemic and pulmonary hemodynamics in patients with pulmonary hypertension secondary to rheumatic mitral valve disease?
Population
21 patients with pulmonary hypertension secondary to rheumatic mitral valve disease undergoing right and…
Design
Case_series
Authors
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Bradykinin primarily affects systemic hemodynamics in mitral PH; leaves open selective pulmonary effects and any therapeutic role.
Does continuous intravenous infusion of synthetic bradykinin alter systemic and pulmonary hemodynamics in patients with pulmonary hypertension secondary to rheumatic mitral valve disease?
Intravenous bradykinin primarily affects systemic vessels and the heart, with secondary mechanical or reflex changes in the pulmonary circulation in patients with pulmonary hypertension due to mitral valve disease.
FREITAS et al. (1966) studied this question.
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