Population
Feline, human, and murine cell lines infected with retroviruses, vesicular stomatitis virus, or…
Comparison
Recombinant human leukocyte interferons… vs Untreated cells and natural human leukocyte…
Design
Preclinical
Authors
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Species-specific IFN potency differences caution against cross-species extrapolation; leaves open optimal hybrid selection for antiviral applications.
Recombinant human leukocyte interferons and their hybrids exhibit varying but proportional antiviral potencies against different viruses across human, feline, and murine cells.
Sen et al. (1984) studied this question.
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