Why the study?
Does celiprolol improve blood pressure reduction compared to propranolol in patients with uncomplicated essential hypertension?
Population
58 patients with uncomplicated essential hypertension (supine diastolic blood pressure range 95-114 mm Hg)
Comparison
Celiprolol 200 or 400 mg single daily oral dose… vs Propranolol 40 or 80 mg twice daily oral dose…
Design
RCT, randomized, double-blind
Follow-up
12 weeks
Authors
Loading...
Supports celiprolol over propranolol for greater BP reduction with less HR slowing; extends comparative beta-blocker data in essential hypertension.
Does celiprolol improve blood pressure reduction compared to propranolol in patients with uncomplicated essential hypertension?
Celiprolol administered once daily provides effective blood pressure reduction comparable to or greater than twice-daily propranolol, with significantly less reduction in heart rate.
Taylor et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: