Why the study?
Does celiprolol improve systemic and forearm hemodynamics compared to metoprolol in hypertensive patients?
Population
20 hypertensive patients
Comparison
Celiprolol (6-week course) vs Metoprolol (6-week course)
Design
RCT, randomized, double-blind
Follow-up
18 weeks
Authors
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Supports beta-blocker selection by hemodynamic profile in hypertension; extends differentiation among subclasses despite equivalent BP reduction.
Does celiprolol improve systemic and forearm hemodynamics compared to metoprolol in hypertensive patients?
Celiprolol and metoprolol achieve similar blood pressure reductions through different hemodynamic mechanisms, with celiprolol reducing peripheral resistance and metoprolol reducing cardiac output.
Trimarco et al. (1987) studied this question.