Why the study?
Does microinjection of kynurenic acid into the NTS reduce pressor responses evoked by arterial chemoreceptor activation in rats?
Population
Chloralose-urethan-anesthetized, mechanically ventilated, paralyzed rats
Comparison
Microinjection of 4 nmol of kynurenic acid, a… vs Control conditions and microinjection of 4 nmol…
Design
Preclinical
Follow-up
25 minutes post-injection
Authors
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Does not inform clinical practice; extends evidence that excitatory amino acid receptors in the NTS mediate chemoreflexes in rats.
Does microinjection of kynurenic acid into the NTS reduce pressor responses evoked by arterial chemoreceptor activation in rats?
Excitatory amino acid receptors within the nucleus tractus solitarius play an important role in mediating arterial chemoreceptor reflexes in rats.
Zhang et al. (1993) studied this question.
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