Key result
Sindbis virus infection was associated with muscle regeneration from previous necrotic lesions in a patient with chronic myalgia, and human myogenic cells were susceptible to SINV infection in vitro.
Population
1 patient with chronic myalgia and arthralgia 6 months after acute Sindbis virus infection, and primary…
Design
Case_report
Follow-up
6 months
Authors
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SINV may contribute to chronic myalgia via muscle regeneration; hypothesis-generating and requires validation in larger cohorts.
Case Report (n=1)
This study provides new insights into the pathological processes of chronic symptoms in SINV infection and demonstrates the susceptibility of human myogenic cells to SINV.
Sane et al. (2012) conducted a case report in Sindbis virus (SINV) infection with chronic myalgia and arthralgia (n=1). Sindbis virus (SINV) infection was evaluated on Muscle pathology and in vitro susceptibility to SINV infection. Sindbis virus infection was associated with muscle regeneration from previous necrotic lesions in a patient with chronic myalgia, and human myogenic cells were susceptible to SINV infection in vitro.
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