Key result
Increased perirenal fat thickness is associated with an unfavorable profile of inflammatory cytokines, atherosclerosis, dyslipidemias, metabolic syndrome, and unfavorable outcomes after nephrectomy.
Why the study?
The burden of CKD in patients with diabetes is high, and recent studies have highlighted the key role of perirenal fat thickness in its pathophysiology.
Hypothesis-generating for perirenal fat assessment pre-nephrectomy; prospective studies needed before clinical adoption.
The burden of chronic kidney disease (CKD) in patients with diabetes is high, and recent studies have highlighted the key role of perirenal fat (PRF) thickness in its pathophysiology (1,2). Indeed, increased PRF thickness has been associated with an unfavorable profile of inflammatory cytokines, atherosclerosis, dyslipidemias, metabolic syndrome, and unfavorable outcomes after nephrectomy (3–11). In this issue of Diabetes , …
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Roever et al. (2021) conducted an editorial in Chronic kidney disease in patients with diabetes. Perirenal fat thickness was evaluated. Increased perirenal fat thickness is associated with an unfavorable profile of inflammatory cytokines, atherosclerosis, dyslipidemias, metabolic syndrome, and unfavorable outcomes after nephrectomy.
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