Key result
Placement of a lucite conduit containing a Hufnagel valve in dogs produced red cell destruction, hemoglobinemia, and markedly shortened red cell survival.
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Permanent bypass of the aortic valve was accomplished in the dog by placing a lucite conduit containing a Hufnagel valve between the left ventricular apex and thoracic aorta. Red cell destruction was produced by the valve in this position and was accompanied by hemoglobinemia, hemoglobinuria, anemia, reticulocytosis and renal hemosiderosis. Red cell survival, as determined with Cr 51 , was markedly shortened.
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Stohlman et al. (1956) studied Aortic valve bypass. Lucite conduit containing a Hufnagel valve was evaluated on Red cell destruction and survival. Placement of a lucite conduit containing a Hufnagel valve in dogs produced red cell destruction, hemoglobinemia, and markedly shortened red cell survival.
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