Key result
The EMIT 2000 digoxin assay demonstrated satisfactory precision and accuracy, a sensitivity of < 0.1 microgram/L, and very low DLIS interference compared to FPIA and RIA.
Why the study?
Does the EMIT 2000 digoxin assay provide accurate and precise measurements with low interference compared to FPIA and RIA?
Population
Plasma samples from patients treated with digoxin, quality-assurance samples, and cord blood samples from…
Comparison
Enzyme-multiplied immunoassay technique digoxin… vs Fluorescence polarization immunoassay and…
Design
Other
Authors
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EMIT 2000 may aid precise digoxin TDM with minimal DLIS interference; leaves open larger validation studies before routine adoption.
Observational
Yes
Does the EMIT 2000 digoxin assay provide accurate and precise measurements with low interference compared to FPIA and RIA?
The EMIT 2000 digoxin assay is a precise, accurate, and sensitive method for therapeutic drug monitoring with minimal interference from digoxin-like immunoreactive substances.
Saccoia et al. (1996) conducted an observational in Patients treated with digoxin. EMIT 2000 digoxin assay vs. Fluorescence polarization immunoassay (FPIA) and radioimmunoassay (RIA) was evaluated on Precision, accuracy, sensitivity, and DLIS interference. The EMIT 2000 digoxin assay demonstrated satisfactory precision and accuracy, a sensitivity of < 0.1 microgram/L, and very low DLIS interference compared to FPIA and RIA.
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