Key result
Encephalomyocarditis virus inoculation in mice resulted in a 90% cumulative incidence of myocarditis, with arrhythmias persisting into the chronic stage in a subset of animals.
Authors
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Supports EMCV mouse model for chronic post-viral arrhythmias; leaves open translation to human myocarditis.
Kishimoto et al. (1983) studied Murine myocarditis (n=86). Encephalomyocarditis (EMC) virus inoculation vs. Baseline (control electrocardiograms) was evaluated on Cumulative incidence of myocarditis. Encephalomyocarditis virus inoculation in mice resulted in a 90% cumulative incidence of myocarditis, with arrhythmias persisting into the chronic stage in a subset of animals.
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