Why the study?
Does atenolol at varying doses (25-100 mg daily) reduce blood pressure and suppress exercise tachycardia compared to 0 mg?
Does atenolol at varying doses (25-100 mg daily) reduce blood pressure and suppress exercise tachycardia compared to 0 mg?
Atenolol achieves near-maximal blood pressure reduction at 25 mg daily, whereas maximal cardiac beta-blockade requires higher doses, indicating divergent dose-response curves.
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Atenolol 25 mg may suffice for BP control; confirms divergent dose-responses for blood pressure versus cardiac beta-blockade.
Marshall et al. (1979) studied this question.
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