Why the study?
Does diltiazem improve metabolic and calcium homeostasis in isolated ischemic rat hearts?
Does diltiazem improve metabolic and calcium homeostasis in isolated ischemic rat hearts?
Diltiazem preserves ATP and maintains cytosolic free calcium levels during myocardial ischemia in a preclinical model, providing mechanistic insight into its cardioprotective effects.
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Hypothesis-generating in rat hearts; leaves open clinical translation for ischemic cardioprotection.
Watts et al. (1990) studied this question.
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