Why the study?
Does quinidine administration affect serum digoxin concentration in patients taking digoxin?
Population
Patients taking digoxin
Design
Editorial
Authors
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Requires digoxin level monitoring with quinidine coadministration; extends prior observations but leaves open magnitude in contemporary populations.
Does quinidine administration affect serum digoxin concentration in patients taking digoxin?
This editorial highlights the clinically significant drug interaction between quinidine and digoxin, which leads to increased serum digoxin concentrations.
J. Thomas Bigger (1979) studied this question.
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