Why the study?
Does bendroflumethiazide compared to propranolol improve blood pressure and side-effect profiles in previously untreated male hypertensives?
Population
106 previously untreated male hypertensives
Comparison
Bendroflumethiazide for 12 to 24 months vs Propranolol for 12 to 24 months
Design
RCT, Randomly selected into two equally large groups
Follow-up
12 to 24 months
Authors
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Bendroflumethiazide matches propranolol for BP control in mild hypertension without metabolic effects; confirms thiazides as safe first-line alternatives in men.
Does bendroflumethiazide compared to propranolol improve blood pressure and side-effect profiles in previously untreated male hypertensives?
Bendroflumethiazide and propranolol are equally effective for blood pressure reduction in mild hypertension with comparable and favorable metabolic and side-effect profiles.
Berglund et al. (1976) studied this question.
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