Why the study?
Does graded treadmill exercise affect regional myocardial blood flow in collateral-dependent myocardium following circumflex coronary artery occlusion in dogs?
Population
11 chronically instrumented awake dogs with acute myocardial infarction produced by abrupt occlusion of the…
Comparison
Graded treadmill exercise 2 weeks after acute… vs Resting state and normally perfused control…
Design
Preclinical
Follow-up
2 weeks
Authors
Loading...
May limit exercise perfusion in heavily infarcted collateral zones; leaves open human translation and clinical exercise guidance.
Does graded treadmill exercise affect regional myocardial blood flow in collateral-dependent myocardium following circumflex coronary artery occlusion in dogs?
The capacity of the coronary collateral circulation to deliver blood to its dependent myocardium during exercise is compromised progressively in proportion to the degree of infarcted myocardium.
Hess et al. (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: