Why the study?
Does exercise increase myocardial blood flow in collateral-dependent myocardium in dogs with chronic coronary artery occlusion?
Population
6 dogs with chronic coronary artery occlusion
Comparison
Two levels of treadmill exercise vs Rest (baseline)
Design
Preclinical
Authors
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Supports exercise perfusion via mature collaterals in canine models; extends rest observations but leaves open human translation.
Does exercise increase myocardial blood flow in collateral-dependent myocardium in dogs with chronic coronary artery occlusion?
In a canine model of chronic coronary occlusion, mature intercoronary collateral vasculature can supply adequate flow at rest and increase flow during exercise similarly to normally perfused myocardium.
Lambert et al. (1977) studied this question.
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