Why the study?
Does ricinoleated vaccine prevent paralysis following poliomyelitis virus inoculation in rhesus monkeys?
Population
Rhesus monkeys
Comparison
5 to 10 subcutaneous or intracutaneous… vs Unvaccinated controls
Design
Preclinical
Authors
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Monkey protection data extend preclinical polio vaccine evidence; leaves open human translation and safety trials.
Does ricinoleated vaccine prevent paralysis following poliomyelitis virus inoculation in rhesus monkeys?
Ricinoleated vaccine provides significant protection against poliomyelitis virus in rhesus monkeys, with intracutaneous administration appearing safer and more effective than subcutaneous injection.
Kolmer et al. (1937) studied this question.
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