Key result
Perindopril monotherapy significantly reduced blood pressure in both African-American and white hypertensive patients (P<0.001), though the magnitude of reduction was greater in white patients.
Why the study?
Does perindopril reduce blood pressure effectively in African-American hypertensive patients compared to white hypertensive patients?
Does perindopril reduce blood pressure effectively in African-American hypertensive patients compared to white hypertensive patients?
p-value: p=<.001
Perindopril monotherapy is an effective and viable initial antihypertensive option for African-American patients, despite a lesser magnitude of blood pressure reduction compared to white patients.
No takes yet. Share an insight, caveat, or question.
May support perindopril as initial therapy in African-American hypertensives; leaves open whether racial BP differences affect outcomes in trials.
Jay N. Cohn (2004) studied Hypertension (n=9,157). Perindopril vs. White patients was evaluated on Reduction of blood pressure (p=<.001). Perindopril monotherapy significantly reduced blood pressure in both African-American and white hypertensive patients (P<0.001), though the magnitude of reduction was greater in white patients.
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